Philips De Schoone Te Rotterdam in 1497

Het Coolsingelziekenhuis te Rotterdam (1839–1900): de ontwikkeling van een stedelijk ziekenhuis in de 19e eeuw

Its Finnish counterpart is more for the scholar. Its strength lies in its use of the inscriptions of doctors, written in both Greek and Latin, to give some idea of their social position, a favourite Finnish theme that goes back to Gummerus. Its conclusion modifies the optimistic conclusions of Kudlien, confirming that there is little evidence for great wealth among physicians, and, equally, non...

`De bevordering en volmaking der proefondervindelijke wijsbegeerte': de rol van het Bataafsch Genootschap te Rotterdam in de geschiedenis van de natuurwetenschappen, geneeskunde en techniek (1769–1988)

For all the obvious hazards and problems of using such a compilation, it is an extraordinary resource. It should surely provide the basis for a much-needed prosopography of the medical trade in the pre-reform era. The sheer proliferation ofnumbers (there are clearly well over 35,000 medical practitioners, in the narrow sense, listed here) provides ample confirmation of the arguments, recently a...

Dmd058636 1493..1497

A large set of Bacillus megaterium CYP102A1 mutants are known to metabolize various drugs to form human metabolites. Omeprazole (OMP), a proton pump inhibitor, has been widely used as an acid inhibitory agent for the treatment of gastric acid hypersecretion disorders. It is primarily metabolized by human CYP2C19 and CYP3A4 to 59-OH OMP and a sulfone product, respectively. It was recently report...

Translation Series No. 1497

Dmd058636 1493..1497

A large set of Bacillus megaterium CYP102A1 mutants are known to metabolize various drugs to form human metabolites. Omeprazole (OMP), a proton pump inhibitor, has been widely used as an acid inhibitory agent for the treatment of gastric acid hypersecretion disorders. It is primarily metabolized by human CYP2C19 and CYP3A4 to 59-OH OMP and a sulfone product, respectively. It was recently report...